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CAS RN 909910-43-6

H3CNNNNSNH

CAS RN 909910-43-6

IUPAC Navn: 3-(6-methylpyridin-2-yl)-N-phenyl-4-(quinolin-4-yl)-1H-pyrazole-1-carbothioamide
Synonymer: 3-(6-methylpyridin-2-yl)-N-phenyl-4-(quinolin-4-yl)pyrazole-1-carbothioamide
Molekylvægt (g/mol): 421.52
Molekylformel: C25H19N5S
InChi Key: HIJMSZGHKQPPJS-UHFFFAOYSA-N
SMILES: CC1=CC=CC(=N1)C1=NN(C=C1C1=C2C=CC=CC2=NC=C1)C(=S)NC1=CC=CC=C1
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1
Kampagner er tilgængelige

Tocris Bioscience™ A 83-01
GREENER_CHOICE

CAS: 909910-43-6 Molekylær formel: C25H19N5S

CAS 909910-43-6
Molekylær formel C25H19N5S
2

A 83-01, TRC

CAS: 909910-43-6 Molekylær formel: C25 H19 N5 S Molekylvægt (g/mol): 421.52 Synonym: A 83-01,3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide IUPAC navn: 3-(6-methyl-2-pyridyl)-N-phenyl-4-(4-quinolyl)pyrazole-1-carbothioamide SMIL: Cc1cccc(n1)c2nn(cc2c3ccnc4ccccc34)C(=S)Nc5ccccc5

Molekylvægt (g/mol) 421.52
CAS 909910-43-6
Synonym A 83-01,3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
SMIL Cc1cccc(n1)c2nn(cc2c3ccnc4ccccc34)C(=S)Nc5ccccc5
IUPAC navn 3-(6-methyl-2-pyridyl)-N-phenyl-4-(4-quinolyl)pyrazole-1-carbothioamide
Molekylær formel C25 H19 N5 S
3
Kampagner er tilgængelige

Tocris Bioscience™ A 83-01
GREENER_CHOICE

A 83-01 synthesized to Ancillary Material Grade

4

STEMCELL Technologies A 83-01

Activin/NODAL/TGF-β pathway inhibitor; Inhibits ALK5, ALK4, and ALK7

ENCOMPASS_PREFERRED
CAS 909910-43-6
Renhed ≥95%
Molekylær formel C25H19N5S
5

A 83-01, MedChemExpress

MedChemExpress A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale A 83-01
Sundhedsfare 1 H302∣H315∣H319∣H335
Formel vægt 421.52
Opløselighedsinformation DMSO : 25 mg/mL (59.31 mM; ultrasonic and warming and heat to 60°C) ∣H2O : < 0.1 mg/mL (insoluble)
Procent renhed 95.0%
Fysisk form Powder
Farve Off-White
Grad Research
Anbefalet opbevaring -20°C, protect from light, stored under nitrogen∣The compound is unstable in solutions, freshly prepared is recommended.
Molekylvægt (g/mol) 421.52
CAS 909910-43-6
Holdbarhed -20°C, protect from light, stored under nitrogen∣The compound is unstable in solutions, freshly prepared is recommended.
SMIL S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5
Renhedsgrad noter Research
Molekylær formel C25H19N5S
Til brug med (applikation) Cancer-Kinase/protease