CAS RN 893990-34-6

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VU 0240551, MedChemExpress

MedChemExpress VU 0240551 is a potent neuronal K-Cl cotransporter KCC2 inhibitor (IC50=560 nM) and is selective versus NKCC1. VU 0240551 also inhibits hERG and L-type Ca2+ channels. VU 0240551 attenuates GABA-induced hyperpolarization of P cells, produces a positive shift in the P cell GABA reversal potential and enhances P cell synaptic transmission.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	VU 0240551
Formel vægt	342.44
Opløselighedsinformation	DMSO : ≥ 50 mg/mL (146.01 mM)
Procent renhed	99.52%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	342.44
CAS	893990-34-6
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(CSC1=NN=C(C2=CC=CC=C2)C=C1)NC3=NC(C)=CS3
Renhedsgrad noter	Research
Molekylær formel	C₁₆H₁₄N₄OS₂

VU 0240551, Tocris Bioscience™

CAS: 893990-34-6 Molekylær formel: C16H14N4OS2 Molekylvægt (g/mol): 342.435 InChI nøgle: WJRWSLORVIHRNX-UHFFFAOYSA-N Synonym: n-4-methyl-2-thiazolyl-2-6-phenyl-3-pyridazinyl thio-acetamide,n-4-methyl-2-thiazolyl-2-6-phenyl-3-pyridazinyl thio acetamide,n-4-methyl-1,3-thiazol-2-yl-2-6-phenylpyridazin-3-yl thio acetamide,n-4-methylthiazol-2-yl-2-6-phenylpyridazin-3-ylthio acetamide,n-4-methyl-1,3-thiazol-2-yl-2-6-phenylpyridazin-3-yl sulfanylacetamide,n-4-methyl-1,3-thiazol-2-yl-2-6-phenylpyridazin-3-yl sulfanyl acetamide,d0m2pp,cid,vu hplc,n-4-methylthiazol-2-yl-2-6-phenylpyridazin-3-yl thio acetamide PubChem CID: 7211972 IUPAC navn: N-(4-methyl-1,3-thiazol-2-yl)-2-(6-phenylpyridazin-3-yl)sulfanylacetamide SMIL: CC1=CSC(=N1)NC(=O)CSC2=NN=C(C=C2)C3=CC=CC=C3

Pris og tilgængelighed
Tekniske data

PubChem CID	7211972
Molekylvægt (g/mol)	342.435
CAS	893990-34-6
Synonym	n-4-methyl-2-thiazolyl-2-6-phenyl-3-pyridazinyl thio-acetamide,n-4-methyl-2-thiazolyl-2-6-phenyl-3-pyridazinyl thio acetamide,n-4-methyl-1,3-thiazol-2-yl-2-6-phenylpyridazin-3-yl thio acetamide,n-4-methylthiazol-2-yl-2-6-phenylpyridazin-3-ylthio acetamide,n-4-methyl-1,3-thiazol-2-yl-2-6-phenylpyridazin-3-yl sulfanylacetamide,n-4-methyl-1,3-thiazol-2-yl-2-6-phenylpyridazin-3-yl sulfanyl acetamide,d0m2pp,cid,vu hplc,n-4-methylthiazol-2-yl-2-6-phenylpyridazin-3-yl thio acetamide
SMIL	CC1=CSC(=N1)NC(=O)CSC2=NN=C(C=C2)C3=CC=CC=C3
IUPAC navn	N-(4-methyl-1,3-thiazol-2-yl)-2-(6-phenylpyridazin-3-yl)sulfanylacetamide
InChI nøgle	WJRWSLORVIHRNX-UHFFFAOYSA-N
Molekylær formel	C16H14N4OS2

CAS RN 893990-34-6

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