CAS RN 869886-67-9

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Ulixertinib, MedChemExpress

MedChemExpress Ulixertinib (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Ulixertinib
Formel vægt	433.33
Opløselighedsinformation	DMSO : 100 mg/mL (230.77 mM; Need ultrasonic)
Procent renhed	98.44%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	433.33
CAS	869886-67-9
Synonym	BVD-523 VRT752271
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C1=CC(C2=CC(NC(C)C)=NC=C2Cl)=CN1)N[C@@H](C3=CC=CC(Cl)=C3)CO
Renhedsgrad noter	Research
Molekylær formel	C₂₁H₂₂Cl₂N₄O₂
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 869886-67-9

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