CAS RN 836620-48-5

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Tocris Bioscience™ AS 1842856

Potent and selective Foxo1 inhibitor; orally bioavailable

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
CAS	836620-48-5
Renhed	98%
Molekylær formel	C₁₈H₂₂FN₃O₃

MedChemExpress AS1842856, a specific Foxo1 inhibitor (IC50=30 nM), potently suppresses autophagy. AS1842856 only reduces the activity of FoxO1 by binding with it, without affecting its transcription and protein expression.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	AS1842856
Sundhedsfare 1	H302∣H410
Formel vægt	347.38
Opløselighedsinformation	DMSO : 5 mg/mL (14.39 mM; ultrasonic and warming and heat to 60°C)
Procent renhed	98.03%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	347.38
CAS	836620-48-5
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C1=CN(CC)C2=C(C(N)=C(F)C(NC3CCCCC3)=C2)C1=O)O
Renhedsgrad noter	Research
Molekylær formel	C₁₈H₂₂FN₃O₃
Til brug med (applikation)	Metabolism-sugar/lipid metabolism

CAS RN 836620-48-5

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Tocris Bioscience™ AS 1842856 Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ AS 1842856