CAS RN 827022-32-2

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Palbociclib monohydrochloride, MedChemExpress

MedChemExpress Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

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Tekniske data

Kemisk navn eller materiale	Palbociclib monohydrochloride
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	483.99
Opløselighedsinformation	H2O : 7.14 mg/mL (14.75 mM; ultrasonic and warming and heat to 60°C) ∣DMSO : 4.63 mg/mL (9.57 mM; ultrasonic and warming and heat to 80°C)
Procent renhed	95.0%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	483.99
CAS	827022-32-2
Synonym	PD 0332991 monohydrochloride
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5.Cl
Renhedsgrad noter	Research
Molekylær formel	C₂₄H₃₀ClN₇O₂
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 827022-32-2

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