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Palbociclib monohydrochloride, MedChemExpress

Artikelnummer. 16487866
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16487866 100 mg
16430568 5 mg
16428108 10 mg
16404027 50 mg
16401326 200 mg
16421926 500 mg
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Artikelnummer. 16487866 Leverandør Medchem Express Leverandørnr. HY50767A

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Beskrivelse

MedChemExpress Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Tekniske data

Kemisk navn eller materiale Palbociclib monohydrochloride
CAS 827022-32-2
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C24H30ClN7O2
Mængde 100 mg
Synonym PD 0332991 monohydrochloride
Opløselighedsinformation H2O : 7.14 mg/mL (14.75 mM; ultrasonic and warming and heat to 60°C) ∣DMSO : 4.63 mg/mL (9.57 mM; ultrasonic and warming and heat to 80°C)
SMIL O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5.Cl
Molekylvægt (g/mol) 483.99
Formel vægt 483.99
Procent renhed 95.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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