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CAS RN 808118-40-3

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1

Tocris Bioscience™ Roxadustat
GREENER_CHOICE

HIF-PH inhibitor; erythropoietic

2

N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine, TRC

CAS: 808118-40-3 Molekylær formel: C19 H16 N2 O5 Molekylvægt (g/mol): 352.34 Synonym: Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-,N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine,(4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycine,ASP 1517,FG 4592,Roxadustat,[[(4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]amino]acetic acid IUPAC navn: 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid SMIL: Cc1nc(C(=O)NCC(=O)O)c(O)c2ccc(Oc3ccccc3)cc12

Molekylvægt (g/mol) 352.34
CAS 808118-40-3
Synonym Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-,N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine,(4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycine,ASP 1517,FG 4592,Roxadustat,[[(4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]amino]acetic acid
SMIL Cc1nc(C(=O)NCC(=O)O)c(O)c2ccc(Oc3ccccc3)cc12
IUPAC navn 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid
Molekylær formel C19 H16 N2 O5
3

Roxadustat, MedChemExpress

MedChemExpress Roxadustat is an oral hypoxia-inducible factor prolyl-hydroxylase inhibitor (HIF-PHI) that promotes erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Roxadustat
Formel vægt 352.34
Opløselighedsinformation DMSO : ≥ 100 mg/mL (283.82 mM) ∣H2O : < 0.1 mg/mL (ultrasonic) (insoluble)
Procent renhed 98.08%
Fysisk form Solid
Farve Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 352.34
CAS 808118-40-3
Synonym FG-4592
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(O)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC3=CC=CC=C3)C=C2)=O
Renhedsgrad noter Research
Molekylær formel C19H16N2O5
Til brug med (applikation) Cancer-programmed cell death