CAS RN 65673-63-4

IUPAC Navn: ethyl (4R)-2-amino-6-bromo-4-[(1S)-1-cyano-2-ethoxy-2-oxoethyl]-4H-chromene-3-carboxylate

Synonymer: ethyl (4R)-2-amino-6-bromo-4-[(1S)-1-cyano-2-ethoxy-2-oxoethyl]-4H-chromene-3-carboxylate

Molekylvægt (g/mol): 409.24

Molekylformel: C17H17BrN2O5

InChi Key: SXJDCULZDFWMJC-YPMHNXCESA-N

SMILES: CCOC(=O)[C@H](C#N)[C@@H]1C2=CC(Br)=CC=C2OC(N)=C1C(=O)OCC

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HA14-1, MedChemExpress

MedChemExpress HA14-1 is a Bcl-2/Bcl-XL antagonist. HA14-1 binds the designated pocket on Bcl-2 with the IC50 of ≈9 μM in competing with the Bcl-2 binding of Flu-BakBH3, and inhibits its function.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	HA14-1
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	409.23
Opløselighedsinformation	DMSO : ≥ 50 mg/mL (122.18 mM)
Procent renhed	98.0%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	409.23
CAS	65673-63-4
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	CCOC(C1=C(N)OC2=CC=C(Br)C=C2[C@@]1([H])[C@H](C#N)C(OCC)=O)=O
Renhedsgrad noter	Research
Molekylær formel	C₁₇H₁₇BrN₂O₅
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 65673-63-4

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