CAS RN 524923-88-4

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JNJ-10229570, MedChemExpress

MedChemExpress JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	JNJ-10229570
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	389.47
Opløselighedsinformation	DMSO : 62.5 mg/mL (160.47 mM; Need ultrasonic)
Procent renhed	98.0%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	389.47
CAS	524923-88-4
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	COC1=C(C=CC=C1)C(N(C2=C(C=CC=C2)OC)S/3)=NC3=N\C4=CC=CC=C4
Renhedsgrad noter	Research
Molekylær formel	C₂₂H₁₉N₃O₂S

CAS RN 524923-88-4

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