CAS RN 501925-31-1

IUPAC Navn: 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methyl-1,2-oxazol-3-yl)urea

Synonymer: 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methyl-1,2-oxazol-3-yl)urea

Molekylvægt (g/mol): 311.72

Molekylformel: C13H14ClN3O4

InChi Key: CEIIEALEIHQDBX-UHFFFAOYSA-N

SMILES: COC1=CC(OC)=C(Cl)C=C1NC(=O)NC1=NOC(C)=C1

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Tocris Bioscience™ PNU 120596

Positive allosteric modulator of α7 nAChRs; active in vivo

Pris og tilgængelighed
Tekniske data

Analyseprocentområde	>99%
Kemisk navn eller materiale	N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea
Anbefalet opbevaring	Desiccate at +4°C
CAS	501925-31-1
Formel vægt	Observed MW: 311.72
Molekylær formel	C₁₃H₁₄ClN₃O₄

MedChemExpress PNU-120596 (NSC 216666) is a potent and selective α7 nAChR positive allosteric modulator (PMA) with an EC50 of 216 nM. PNU-120596 is inactive against α4β2, α3β4, and α9α10 nAChRs. PNU-120596 has the potential for psychiatric and neurological disorders research.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	PNU-120596
Sundhedsfare 1	H302∣H315∣H320∣H335
Formel vægt	311.72
Opløselighedsinformation	DMSO : 50 mg/mL (160.40 mM; Need ultrasonic)
Procent renhed	95.0%
Fysisk form	Solid
Farve	Gray
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	311.72
CAS	501925-31-1
Synonym	NSC 216666
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC1=CC(Cl)=C(C=C1OC)OC)NC2=NOC(C)=C2
Renhedsgrad noter	Research
Molekylær formel	C₁₃H₁₄ClN₃O₄
Til brug med (applikation)	Neuroscience-Neuromodulation

CAS RN 501925-31-1

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Tocris Bioscience™ PNU 120596 Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ PNU 120596