CAS RN 444723-13-1
IUPAC Navn:
4-{[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino}-N,N-diethylbenzamide
Synonymer:
4-{[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino}-N,N-diethylbenzamide
Molekylvægt (g/mol):
422.53
Molekylformel:
C23H30N6O2
InChi Key:
XHEQSRJCJTWWAH-UHFFFAOYSA-N
SMILES:
CCN(CC)C(=O)C1=CC=C(NC2=NC(OCC3CCCCC3)=C3NC=NC3=N2)C=C1
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Resultater
1
Tocris Bioscience™ NU 6140
CAS: 444723-13-1 Molekylær formel: C23H30N6O2
2
NU6140, MedChemExpress
MedChemExpress NU6140 is a selective CDK2-cyclin A inhibitor (IC50, 0.41 μM), exhibits 10- to 36-fold selectivity over other CDKs. NU6140 also potently inhibits Aurora A and Aurora B, with IC50s of 67 and 35 nM, respectively. Enhances the apoptotic effect, with anti-cancer activity.
