CAS RN 383907-43-5

IUPAC Navn: 6-chloro-7-{[2-(morpholin-4-yl)ethyl]amino}-5,8-dihydroquinoline-5,8-dione

Synonymer: 6-chloro-7-{[2-(morpholin-4-yl)ethyl]amino}quinoline-5,8-dione

Molekylvægt (g/mol): 321.76

Molekylformel: C15H16ClN3O3

InChi Key: BMKPVDQDJQWBPD-UHFFFAOYSA-N

SMILES: ClC1=C(NCCN2CCOCC2)C(=O)C2=C(C=CC=N2)C1=O

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NSC 663284, MedChemExpress

MedChemExpress NSC 663284 (DA-3003-1) is a potent, cell-permeable, and irreversible Cdc25 dual specificity phosphatase inhibitor, has an IC50 for Cdc25B2 of 0.21 μM. NSC 663284 exhibits mixed competitive kinetics against Cdc25A, Cdc25B(2), and Cdc25C with Ki values of 29, 95, and 89 nM, respectively. NSC 663284 inhibits NSD2 (IC50 of 170 nM) through a direct interaction with the catalytic SET domain (Kd of 370 nM).

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	NSC 663284
Formel vægt	321.76
Opløselighedsinformation	DMSO : ≥ 150 mg/mL (466.19 mM)
Procent renhed	99.87%
Fysisk form	Solid
Farve	Red
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	321.76
CAS	383907-43-5
Synonym	DA-3003-1
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C(Cl)=C1NCCN2CCOCC2)C3=C(N=CC=C3)C1=O
Renhedsgrad noter	Research
Molekylær formel	C₁₅H₁₆ClN₃O₃
Til brug med (applikation)	Cancer-programmed cell death

Thermo Scientific Chemicals NSC 663284

CAS: 383907-43-5 Molekylær formel: C15H16ClN3O3,C15H16ClN3O3 Synonym: 6-Chloro-7-(2-morpholin-4-yl-ethylamino)quinoline-5,8-dione; Cdc25 Phosphatase Inhibitor II

Pris og tilgængelighed
Tekniske data

CAS	383907-43-5
Synonym	6-Chloro-7-(2-morpholin-4-yl-ethylamino)quinoline-5,8-dione; Cdc25 Phosphatase Inhibitor II
Molekylær formel	C15H16ClN3O3,C15H16ClN3O3

Tocris Bioscience™ NSC 663284

Pris og tilgængelighed

CAS RN 383907-43-5

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