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NSC 663284, MedChemExpress

Artikelnummer. 16495497
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16495497 5 mg
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Artikelnummer. 16495497 Leverandør Medchem Express Leverandørnr. HY100034

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Beskrivelse

MedChemExpress NSC 663284 (DA-3003-1) is a potent, cell-permeable, and irreversible Cdc25 dual specificity phosphatase inhibitor, has an IC50 for Cdc25B2 of 0.21 μM. NSC 663284 exhibits mixed competitive kinetics against Cdc25A, Cdc25B(2), and Cdc25C with Ki values of 29, 95, and 89 nM, respectively. NSC 663284 inhibits NSD2 (IC50 of 170 nM) through a direct interaction with the catalytic SET domain (Kd of 370 nM).

NSC 663284 (DA-3003-1) is a potent, cell-permeable, and irreversible Cdc25 dual specificity phosphatase inhibitor, has an IC50 for Cdc25B2 of 0.21 μM. NSC 663284 exhibits mixed competitive kinetics against Cdc25A, Cdc25B(2), and Cdc25C with Ki values of 29, 95, and 89 nM, respectively. NSC 663284 inhibits NSD2 (IC50 of 170 nM) through a direct interaction with the catalytic SET domain (Kd of 370 nM).

Tekniske data

Kemisk navn eller materiale NSC 663284
Fysisk form Solid
CAS 383907-43-5
Farve Red
Mængde 5 mg
Renhedsgrad noter Research
Molekylær formel C15H16ClN3O3
Til brug med (applikation) Cancer-programmed cell death
Synonym DA-3003-1
Opløselighedsinformation DMSO : ≥ 150 mg/mL (466.19 mM)
SMIL O=C(C(Cl)=C1NCCN2CCOCC2)C3=C(N=CC=C3)C1=O
Molekylvægt (g/mol) 321.76
Formel vægt 321.76
Procent renhed 99.87%
Grad Research
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Research purposes only

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