CAS RN 310456-65-6

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IMR-1, MedChemExpress

MedChemExpress IMR-1 is a novel class of Notch inhibitor targeting the transcriptional activation with an IC50 of 26 μM. IMR-1 prevents the recruitment of Mastermind-like 1 (Maml1) to the Notch Ternary Complex (NTC) on chromatin, inhibits Notch target gene transcription and dramatically inhibits tumor growth.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	IMR-1
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	353.41
Opløselighedsinformation	DMSO : ≥ 100 mg/mL (282.96 mM)
Procent renhed	98.88%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	353.41
CAS	310456-65-6
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(OCC)COC1=CC=C(/C=C(SC(N2)=S)\C2=O)C=C1OC
Renhedsgrad noter	Research
Molekylær formel	C₁₅H₁₅NO₅S₂
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 310456-65-6

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