CAS RN 288591-93-5

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MedChemExpress Leu-AMS (compound 6), a leucine analogue, is a potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM, which inhibits the catalytic activity of LRS but did not affect the leucine-induced mTORC1 activation. Leu-AMS shows cytotoxicity in cancer cells and normal cells, and inhibits the growth of bacteria.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Leu-AMS
Formel vægt	459.48
Opløselighedsinformation	DMSO : ≥ 49.17 mg/mL (107.01 mM)
Procent renhed	97.04%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	459.48
CAS	288591-93-5
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O[C@@H]([C@H]([C@H](N1C=NC2=C1N=CN=C2N)O3)O)[C@H]3COS(=O)(NC([C@@H](N)CC(C)C)=O)=O
Renhedsgrad noter	Research
Molekylær formel	C₁₆H₂₅N₇O₇S
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 288591-93-5

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