CAS RN 280744-09-4

IUPAC Navn: 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

Synonymer: 3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)-1H-pyrrole-2,5-dione

Molekylvægt (g/mol): 371.22

Molekylformel: C19H12Cl2N2O2

InChi Key: JCSGFHVFHSKIJH-UHFFFAOYSA-N

SMILES: CN1C=C(C2=CC=CC=C12)C1=C(C(=O)NC1=O)C1=CC=C(Cl)C=C1Cl

1 – 3 af 3 Resultater

CAS: 280744-09-4 Molekylær formel: C19H12Cl2N2O2

CAS	280744-09-4
Molekylær formel	C19H12Cl2N2O2

WNT pathway activator; Inhibits GSK3α and GSK3β

MedChemExpress SB 216763 is potent, selective and ATP-competitive GSK-3 inhibitor with IC50s of 34.3 nM for both GSK-3α and GSK-3β.

Kemisk navn eller materiale	SB 216763
Sundhedsfare 1	H315∣H319∣H335
Formel vægt	371.22
Opløselighedsinformation	DMSO : 100 mg/mL (269.38 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
Procent renhed	98.92%
Fysisk form	Powder
Farve	Orange Red
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	371.22
CAS	280744-09-4
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC1=O)C(C2=CC=C(C=C2Cl)Cl)=C1C3=CN(C4=C3C=CC=C4)C
Renhedsgrad noter	Research
Molekylær formel	C₁₉H₁₂Cl₂N₂O₂
Til brug med (applikation)	Cancer-Kinase/protease