CAS RN 2306178-56-1

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DMX-5804, MedChemExpress

MedChemExpress DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96). DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice.

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Tekniske data

Kemisk navn eller materiale	DMX-5804
Formel vægt	361.39
Opløselighedsinformation	DMSO : 125 mg/mL (345.89 mM; Need ultrasonic)
Procent renhed	99.49%
Fysisk form	Powder
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	361.39
CAS	2306178-56-1
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C1NC=NC2=C1C(C3=CC=C(OCCOC)C=C3)=CN2C4=CC=CC=C4
Renhedsgrad noter	Research
Molekylær formel	C₂₁H₁₉N₃O₃
Til brug med (applikation)	COVID-19-immunoregulation

CAS RN 2306178-56-1

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