CAS RN 2196204-23-4

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AZ1495, MedChemExpress

MedChemExpress AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC50 values of 0.005 μM and 0.023 μM, respectively. AZ1495 has IRAK4 inhibition with a Kd value of 0.0007 μM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL).

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	AZ1495
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	385.5
Opløselighedsinformation	DMSO : 10 mg/mL (25.94 mM; Need ultrasonic)
Procent renhed	98.0%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	385.5
CAS	2196204-23-4
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	C1(C(C2CCOCC2)=CN3)=C3N=CN=C1N[C@@H]4CC[C@@H](N5CCOCC5)CC4
Renhedsgrad noter	Research
Molekylær formel	C₂₁H₃₁N₅O₂
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 2196204-23-4

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