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AZ1495, MedChemExpress

Artikelnummer. 16495296
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100 mg
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5mg
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Artikelnummer. Mængde unitSize
16495296 100 mg -
16493056 25 mg 25mg
16437127 5 mg 5mg
16424408 10 mg -
16420727 50 mg -
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Artikelnummer. 16495296 Leverandør Medchem Express Leverandørnr. HY111101

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Beskrivelse

MedChemExpress AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC50 values of 0.005 μM and 0.023 μM, respectively. AZ1495 has IRAK4 inhibition with a Kd value of 0.0007 μM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL).

AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC50 values of 0.005 μM and 0.023 μM, respectively. AZ1495 has IRAK4 inhibition with a Kd value of 0.0007 μM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL).

Tekniske data

Kemisk navn eller materiale AZ1495
Fysisk form Solid
CAS 2196204-23-4
Farve White
Mængde 100 mg
Renhedsgrad noter Research
Molekylær formel C21H31N5O2
Til brug med (applikation) Cancer-Kinase/protease
Opløselighedsinformation DMSO : 10 mg/mL (25.94 mM; Need ultrasonic)
SMIL C1(C(C2CCOCC2)=CN3)=C3N=CN=C1N[C@@H]4CC[C@@H](N5CCOCC5)CC4
Molekylvægt (g/mol) 385.5
Formel vægt 385.5
Procent renhed 98.0%
Grad Research
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Research purposes only

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