CAS RN 2093388-62-4

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BETd-260, MedChemExpress

MedChemExpress BETd-260 (ZBC 260) is a PROTAC connected by ligands for Cereblon and BET, with as low as 30 pM against BRD4 protein in RS4;11 leukemia cell line. BETd-260 potently suppresses cell viability and robustly induces apoptosis in hepatocellular carcinoma (HCC) cells.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	BETd-260
Formel vægt	798.89
Opløselighedsinformation	DMSO : 25 mg/mL (31.29 mM; Need ultrasonic)
Procent renhed	98.04%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	-80°C, protect from light, stored under nitrogen
Molekylvægt (g/mol)	798.89
CAS	2093388-62-4
Synonym	ZBC 260
Holdbarhed	-80°C, protect from light, stored under nitrogen
SMIL	CCN1N=C(C2CC2)C=C1NC3=NC(C(NCCCCCC4=CC=CC5=C4CN(C6C(NC(CC6)=O)=O)C5=O)=O)=NC7=C3C8=CC(OC)=C(C9=C(C)ON=C9C)C=C8N7
Renhedsgrad noter	Research
Molekylær formel	C₄₃H₄₆N₁₀O₆
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 2093388-62-4

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