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CH3SOONNNNHNO

CAS RN 2083627-02-3

IUPAC Navn: N-[(furan-2-yl)methyl]-8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine
Synonymer: N-(furan-2-ylmethyl)-8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine
Molekylvægt (g/mol): 369.4
Molekylformel: C17H15N5O3S
InChi Key: DYIRSNMPIZZNBK-UHFFFAOYSA-N
SMILES: CS(=O)(=O)C1=CC=C(C=C1)C1=CN=C(NCC2=CC=CO2)N2C=NN=C12
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2

Tocris Bioscience™ EED 226
GREENER_CHOICE

Potent and selective EED inhibitor

Kemisk navn eller materiale N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine
Anbefalet opbevaring Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
CAS 2083627-02-3
Mål EED
Molekylær formel C17H15N5O3S
3

EED226, MedChemExpress

MedChemExpress EED226 is a polycomb repressive complex 2 (PRC2) inhibitor, which binds to the K27me3-pocket on embryonic ectoderm development (EED) and shows strong antitumor activity in xenograft mice model. EED226 is a potent, selective, and orally bioavailable EED inhibitor. EED226 inhibits PRC2 with an IC50 of 23.4 nM when the H3K27me0 peptide is used as a substrate in the in vitro enzymatic assays.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale EED226
Formel vægt 369.4
Opløselighedsinformation DMSO : ≥ 29 mg/mL (78.51 mM)
Procent renhed 98.61%
Fysisk form Solid
Farve Off-White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 369.4
CAS 2083627-02-3
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=S(C1=CC=C(C2=CN=C(NCC3=CC=CO3)N4C2=NN=C4)C=C1)(C)=O
Renhedsgrad noter Research
Molekylær formel C17H15N5O3S
Til brug med (applikation) Cancer-programmed cell death