CAS RN 2070015-22-2

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OSU-T315, MedChemExpress

MedChemExpress OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain). OSU-T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase-dependent apoptosis in an ILK-independent manner. OSU-T315 causes cell death through apoptosis and autophagy.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	OSU-T315
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	533.59
Opløselighedsinformation	DMSO : ≥ 260 mg/mL (487.27 mM)
Procent renhed	98.0%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	533.59
CAS	2070015-22-2
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC)CCC1=CC(C2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)=NN1C4=CC=C(N5CCNCC5)C=C4
Renhedsgrad noter	Research
Molekylær formel	C₃₀H₃₀F₃N₅O
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 2070015-22-2

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