CAS RN 202592-23-2

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JQ-1 (carboxylic acid), MedChemExpress

MedChemExpress JQ-1 carboxylic acid, a type of (+)-JQ-1 derivative, is a potent BET bromodomain inhibitor for downregulating PD-L1 expression on the surface of tumor cells. JQ-1 carboxylic acid can be used as a precursor to synthesize PROTACs, which targets BET bromodomains.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	JQ-1 (carboxylic acid)
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	400.88
Opløselighedsinformation	DMSO : 31.25 mg/mL (77.95 mM; ultrasonic and warming and heat to 60°C)
Procent renhed	98.01%
Fysisk form	Powder
Farve	Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	400.88
CAS	202592-23-2
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	ClC1=CC=C(C(C2=C(N3C4=NN=C3C)SC(C)=C2C)=N[C@H]4CC(O)=O)C=C1
Renhedsgrad noter	Research
Molekylær formel	C₁₉H₁₇ClN₄O₂S
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 202592-23-2

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