CAS RN 1952251-28-3

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TAK-659 hydrochloride, MedChemExpress

MedChemExpress TAK-659 hydrochloride is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. TAK-659 hydrochloride induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL).

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	TAK-659 hydrochloride
Formel vægt	380.85
Opløselighedsinformation	H2O : 2 mg/mL (5.25 mM; ultrasonic and adjust pH to 3 with HCl) ∣DMSO : < 1 mg/mL (insoluble or slightly soluble)
Procent renhed	98.13%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molekylvægt (g/mol)	380.85
CAS	1952251-28-3
Holdbarhed	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
SMIL	FC1=C(N[C@@H]2CCCC[C@@H]2N)N=C(C3=CN(C)N=C3)C4=C1CNC4=O.Cl
Renhedsgrad noter	Research
Molekylær formel	C₁₇H₂₂ClFN₆O
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1952251-28-3

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