CAS RN 1883863-52-2

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dBET57, MedChemExpress

MedChemExpress dBET57 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology. dBET57 mediates recruitment to the CRL4Cereblon E3 ubiquitin ligase, with a DC50/5h of 500 nM for BRD4BD1, and is inactive on BRD4BD2.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	dBET57
Formel vægt	699.18
Opløselighedsinformation	DMSO : 250 mg/mL (357.56 mM; Need ultrasonic)
Procent renhed	99.66%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molekylvægt (g/mol)	699.18
CAS	1883863-52-2
Holdbarhed	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
SMIL	O=C(NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4
Renhedsgrad noter	Research
Molekylær formel	C₃₄H₃₁ClN₈O₅S
Til brug med (applikation)	Neuroscience-Neuromodulation

CAS RN 1883863-52-2

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