CAS RN 1797406-69-9

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Tocris Bioscience™ MZ 1

(+)-JQ1 based Degrader (PROTAC™) that selectively degrades BRD4

Pris og tilgængelighed

MedChemExpress MZ 1 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. MZ 1 potently and rapidly induces reversible, long-lasting, and selective removal of BRD4 over BRD2 and BRD3. Kds of 382/120, 119/115, and 307/228 nM for BRD4 BD1/2, BRD3 BD1/2, and BRD2 BD1/2, respectively.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	MZ 1
Sundhedsfare 1	H315∣H317∣H318∣H334∣H335∣H341∣H361∣H370∣H413
Formel vægt	1002.64
Opløselighedsinformation	DMSO : 100 mg/mL (99.74 mM; Need ultrasonic)
Procent renhed	95.21%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	-20°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molekylvægt (g/mol)	1002.64
CAS	1797406-69-9
Holdbarhed	-20°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
SMIL	CC1=C(C)SC2=C1C(C3=CC=C(Cl)C=C3)=N[C@@H](CC(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@@H](O)C4)C(NCC5=CC=C(C6=C(N=CS6)C)C=C5)=O)=O)=O)=O)C7=NN=C(C)N27
Renhedsgrad noter	Research
Molekylær formel	C₄₉H₆₀ClN₉O₈S₂
Til brug med (applikation)	Cancer-programmed cell death

Tocris Bioscience™ MZ 1

(+)-JQ1 based Degrader (PROTAC™) that selectively degrades BRD4

Pris og tilgængelighed

CAS RN 1797406-69-9

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Tocris Bioscience™ MZ 1 Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ MZ 1 Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ MZ 1

Tocris Bioscience™ MZ 1