CAS RN 1620574-24-4

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DLK-IN-1, MedChemExpress

MedChemExpress DLK-IN-1 is a selective, orally active inhibitor of dual leucine zipper kinase (DLK, MAP3K12), with a Ki of 3 nM. DLK-IN-1 retains excellent CNS penetration and is well tolerated following multiple days of dosing at concentrations that exceed those required for DLK inhibition in the brain. DLK-IN-1 has activity in a model of Alzheimer’s Disease.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	DLK-IN-1
Formel vægt	423.43
Opløselighedsinformation	DMSO : 62.5 mg/mL (147.60 mM; Need ultrasonic)
Procent renhed	99.41%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	423.43
CAS	1620574-24-4
Holdbarhed	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	CC(N1C([C@@H]2[C@]3([H])[C@@]2([H])CN(C4COC4)C3)=CC(C5=CN=C(N)C(OC(F)(F)F)=C5)=N1)C
Renhedsgrad noter	Research
Molekylær formel	C₂₀H₂₄F₃N₅O₂
Til brug med (applikation)	Neuroscience-Neurodegeneration

CAS RN 1620574-24-4

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