CAS RN 1558021-37-6

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TP0463518, MedChemExpress

MedChemExpress TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	TP0463518
Formel vægt	431.83
Opløselighedsinformation	DMSO : ≥ 125 mg/mL (289.47 mM)
Procent renhed	98.02%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	431.83
CAS	1558021-37-6
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	ClC(C=C1)=CC=C1OC2=NC=C(CN3C(C(C(NCC(O)=O)=O)=C(O)CC3)=O)C=C2
Renhedsgrad noter	Research
Molekylær formel	C₂₀H₁₈ClN₃O₆
Til brug med (applikation)	Metabolism-sugar/lipid metabolism

CAS RN 1558021-37-6

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