CAS RN 1523406-39-4

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SAR405, MedChemExpress

MedChemExpress SAR405 is a first-in-class, selective, and ATP-competitive PI3K class III (PIK3C3) isoform Vps34 inhibitor (IC50=1.2 nM; Kd=1.5 nM). SAR405 inhibits autophagy induced either by starvation or by mTOR inhibition. Anticancer activity.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	SAR405
Formel vægt	443.85
Opløselighedsinformation	DMSO : ≥ 27 mg/mL (60.83 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Procent renhed	97.03%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	443.85
CAS	1523406-39-4
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C1N(C2=NC(N3[C@H](C)COCC3)=C1)CC[C@@H](C(F)(F)F)N2CC4=CC(Cl)=CN=C4
Renhedsgrad noter	Research
Molekylær formel	C₁₉H₂₁ClF₃N₅O₂
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1523406-39-4

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