CAS RN 148741-30-4

IUPAC Navn: (2E)-3-amino-2-[(3,5-di-tert-butyl-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-3-sulfanylprop-2-enenitrile

Synonymer: (2E)-3-amino-2-[(3,5-di-tert-butyl-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-3-sulfanylprop-2-enenitrile

Molekylvægt (g/mol): 316.46

Molekylformel: C18H24N2OS

InChi Key: LCUMYVYIHXYBIA-FOWTUZBSSA-N

SMILES: CC(C)(C)C1=CC(=C\C(C#N)=C(\N)S)C=C(C1=O)C(C)(C)C

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Tyrphostin AG 879, MedChemExpress

MedChemExpress Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC50 of 10 μM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 μM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Tyrphostin AG 879
Sundhedsfare 1	H302
Formel vægt	316.46
Opløselighedsinformation	DMSO : 50 mg/mL (158.00 mM; Need ultrasonic)
Procent renhed	99.54%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	316.46
CAS	148741-30-4
Synonym	AG 879
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	S=C(N)/C(C#N)=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1
Renhedsgrad noter	Research
Molekylær formel	C₁₈H₂₄N₂OS
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 148741-30-4

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