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Tyrphostin AG 879, MedChemExpress

Artikelnummer. 16478018
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16478018 10 mg
16470478 5 mg
16443736 25 mg
16413947 50 mg
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Artikelnummer. 16478018 Leverandør Medchem Express Leverandørnr. HY20878

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Beskrivelse

MedChemExpress Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC50 of 10 μM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 μM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity.

Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC50 of 10 μM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 μM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity.

Tekniske data

Kemisk navn eller materiale Tyrphostin AG 879
CAS 148741-30-4
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C18H24N2OS
Mængde 10 mg
Synonym AG 879
Opløselighedsinformation DMSO : 50 mg/mL (158.00 mM; Need ultrasonic)
SMIL S=C(N)/C(C#N)=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1
Molekylvægt (g/mol) 316.46
Formel vægt 316.46
Procent renhed 99.54%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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