CAS RN 1448169-71-8

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MedChemExpress Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM).

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Futibatinib
Formel vægt	418.45
Opløselighedsinformation	DMSO : ≥ 29 mg/mL (69.30 mM)
Procent renhed	98.02%
Fysisk form	Powder
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	418.45
CAS	1448169-71-8
Synonym	TAS-120
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C=C)N(C1)CC[C@@H]1N(N=C2C#CC3=CC(OC)=CC(OC)=C3)C4=C2C(N)=NC=N4
Renhedsgrad noter	Research
Molekylær formel	C₂₂H₂₂N₆O₃
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1448169-71-8

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