CAS RN 1439901-97-9

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Tirabrutinib hydrochloride, MedChemExpress

MedChemExpress Tirabrutinib (ONO-4059) hydrochloride is an orally active Bruton’s Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib hydrochloride irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib hydrochloride can be used in studies of autoimmune diseases and hematological malignancies.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Tirabrutinib hydrochloride
Formel vægt	490.94
Opløselighedsinformation	DMSO : 100 mg/mL (203.69 mM; Need ultrasonic)
Procent renhed	98.0%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	490.94
CAS	1439901-97-9
Synonym	ONO-4059 hydrochlorideGS-4059 hydrochloride
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	O=C1N(C2=CC=C(OC3=CC=CC=C3)C=C2)C4=C(N)N=CN=C4N1[C@H]5CN(C(C#CC)=O)CC5.[H]Cl
Renhedsgrad noter	Research
Molekylær formel	C₂₅H₂₃ClN₆O₃
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1439901-97-9

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