CAS RN 1434048-34-6

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Fenebrutinib, MedChemExpress

MedChemExpress Fenebrutinib (GDC-0853) is a potent, selective, orally available, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with Kis of 0.91 nM, 1.6, 1.3, 12.6, and 3.4 nM for WT Btk, and the C481S, C481R, T474I, T474M mutants. Fenebrutinib has the potential for rheumatoid arthritis and systemic lupus erythematosus research.

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Tekniske data

Kemisk navn eller materiale	Fenebrutinib
Sundhedsfare 1	H315∣H317∣H318∣H334∣H335∣H341∣H361∣H370∣H413
Formel vægt	664.8
Opløselighedsinformation	DMSO : ≥ 23 mg/mL (34.60 mM)
Procent renhed	98.06%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molekylvægt (g/mol)	664.8
CAS	1434048-34-6
Synonym	GDC-0853
Holdbarhed	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
SMIL	O=C1C(NC(C=C2)=NC=C2N3CCN(C4COC4)C[C@@H]3C)=CC(C5=CC=NC(N6C(C7=CC(CC(C)(C)C8)=C8N7CC6)=O)=C5CO)=CN1C
Renhedsgrad noter	Research
Molekylær formel	C₃₇H₄₄N₈O₄
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1434048-34-6

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