CAS RN 1360614-48-7

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Necrosulfonamide, MedChemExpress

MedChemExpress Necrosulfonamide is a necroptosis inhibitor acting by selectively targeting the mixed lineage kinase domain-like protein (MLKL). Necrosulfonamide prevents MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors. MLKL is a critical substrate of RIP3 during the induction of necrosis.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Necrosulfonamide
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	461.47
Opløselighedsinformation	DMSO : ≥ 28 mg/mL (60.68 mM)
Procent renhed	98.0%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	461.47
CAS	1360614-48-7
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC1=CC=C(S(=O)(NC2=NC=CN=C2OC)=O)C=C1)/C=C/C3=CC=C([N+]([O-])=O)S3.[(E)]
Renhedsgrad noter	Research
Molekylær formel	C₁₈H₁₅N₅O₆S₂
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1360614-48-7

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