CAS RN 1354799-87-3

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Ilginatinib maleate, MedChemExpress

MedChemExpress Ilginatinib maleate (NS-018 maleate) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0.72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM).

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Ilginatinib maleate
Formel vægt	505.5
Opløselighedsinformation	DMSO : ≥ 30 mg/mL (59.35 mM) ∣H2O : 1 mg/mL (1.98 mM; Need ultrasonic)
Procent renhed	97.04%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	505.5
CAS	1354799-87-3
Synonym	NS-018 maleate
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	CN1N=CC(C2=CC(N[C@H](C3=CC=C(F)C=C3)C)=NC(NC4=NC=CN=C4)=C2)=C1.O=C(O)/C=C\C(O)=O
Renhedsgrad noter	Research
Molekylær formel	C₂₅H₂₄FN₇O₄
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1354799-87-3

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