CAS RN 1310726-60-3

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Tocris Bioscience™ Upadacitinib

JAK1-selective inhibitor

Pris og tilgængelighed

Upadacitinib, MedChemExpress

MedChemExpress Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Upadacitinib
Sundhedsfare 1	H315∣H319∣H335
Formel vægt	380.37
Opløselighedsinformation	DMSO : ≥ 22 mg/mL (57.84 mM) ∣H2O : < 0.1 mg/mL (insoluble)
Procent renhed	98.56%
Fysisk form	Powder
Farve	Gray
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	380.37
CAS	1310726-60-3
Synonym	ABT-494
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(N1C[C@@H](CC)[C@@H](C2=CN=C3C=NC(NC=C4)=C4N32)C1)NCC(F)(F)F
Renhedsgrad noter	Research
Molekylær formel	C₁₇H₁₉F₃N₆O
Til brug med (applikation)	COVID-19-immunoregulation

CAS RN 1310726-60-3

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Tocris Bioscience™ Upadacitinib Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ Upadacitinib