CAS RN 1217486-61-7

IUPAC Navn: N1-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide

Synonymer: N1-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide

Molekylvægt (g/mol): 441.47

Molekylformel: C19H22F3N5O2S

InChi Key: STUWGJZDJHPWGZ-UHFFFAOYNA-N

SMILES: CC1=C(SC(NC(=O)N2CCCC2C(N)=O)=N1)C1=CC(=NC=C1)C(C)(C)C(F)(F)F

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Thermo Scientific™ Alpelisib, 95 %

Pris og tilgængelighed

Alpelisib, MedChemExpress

MedChemExpress Alpelisib (BYL-719) is a potent, selective, and orally active PI3Kα inhibitor. Alpelisib (BYL-719) shows efficacy in targeting PIK3CA-mutated cancer. Alpelisib (BYL-719) also inhibits p110α/p110γ/p110δ/p110β with IC50s of 5/250/290/1200 nM, respectively. Antineoplastic activity.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Alpelisib
Formel vægt	441.47
Opløselighedsinformation	DMSO : 83.33 mg/mL (188.76 mM; Need ultrasonic)
Procent renhed	96.33%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	441.47
CAS	1217486-61-7
Synonym	BYL-719
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	CC(N=C(S1)NC(N2CCC[C@H]2C(N)=O)=O)=C1C3=CC(C(C)(C(F)(F)F)C)=NC=C3
Renhedsgrad noter	Research
Molekylær formel	C₁₉H₂₂F₃N₅O₂S
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1217486-61-7

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