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CAS RN 1211441-98-3

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1

Tocris Bioscience™ Ribociclib
GREENER_CHOICE

Dual cdk4/cdk6 inhibitor; orally bioavailable

2

LEE 011, TRC

CAS: 1211441-98-3 Molekylær formel: C23 H30 N8 O Molekylvægt (g/mol): 434.54 Synonym: 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxamide, 7-cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-,7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide,Kisqali,LEE 011,LEE 011A,Ribociclib IUPAC navn: 7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide SMIL: CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N4CCNCC4)nc2n1C5CCCC5

Molekylvægt (g/mol) 434.54
CAS 1211441-98-3
Synonym 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxamide, 7-cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-,7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide,Kisqali,LEE 011,LEE 011A,Ribociclib
SMIL CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N4CCNCC4)nc2n1C5CCCC5
IUPAC navn 7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide
Molekylær formel C23 H30 N8 O
3

Ribociclib, MedChemExpress

MedChemExpress Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Ribociclib
Formel vægt 434.54
Opløselighedsinformation DMSO : 20 mg/mL (46.03 mM; Need ultrasonic)
Procent renhed 99.52%
Fysisk form Powder
Farve Light Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 434.54
CAS 1211441-98-3
Synonym LEE011
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5
Renhedsgrad noter Research
Molekylær formel C23H30N8O
Til brug med (applikation) Cancer-Kinase/protease