CAS RN 1062169-56-5

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MedChemExpress WYE-354 is an ATP-competitive mTOR inhibitor with an IC50 of 5 nM. WYE-354 also inhibits PI3Kα and PI3Kγ with IC50s of 1.89 μM and 7.37 μM, respectively. WYE-354 inhibits both mTORC1 and mTORC2. WYE-354 induces autophagy activation in vitro.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	WYE-354
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	495.53
Opløselighedsinformation	DMSO : 6.67 mg/mL (13.46 mM; Need ultrasonic)
Procent renhed	98.0%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	495.53
CAS	1062169-56-5
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	COC(NC1=CC=C(C=C1)C2=NC3=C(C(N4CCOCC4)=N2)C=NN3C5CCN(CC5)C(OC)=O)=O
Renhedsgrad noter	Research
Molekylær formel	C₂₄H₂₉N₇O₅
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1062169-56-5

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