CAS RN 1026785-55-6

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MedChemExpress Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo-initiated RNA synthesis.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Lomibuvir
Formel vægt	445.61
Opløselighedsinformation	DMSO : 100 mg/mL (224.41 mM; Need ultrasonic)
Procent renhed	98.97%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	445.61
CAS	1026785-55-6
Synonym	VX-222
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C1=C(N([C@@H]2CC[C@@H](O)CC2)C([C@H]3CC[C@H](C)CC3)=O)C=C(C#CC(C)(C)C)S1)O
Renhedsgrad noter	Research
Molekylær formel	C₂₅H₃₅NO₄S
Til brug med (applikation)	COVID-19-anti-virus

CAS RN 1026785-55-6

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