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Biotin og derivater

Organiske heterocykliske forbindelser og derivater, der består af en ureidoring og en tetrahydrothiophenring; ureido indeholder radikalet: NH2CONH− og tetrahydrothiophen er en femleddet ring bestående af fire carbonatomer og et svovlatom.

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Thermo Scientific Chemicals D(+)-biotin, 98 %

CAS: 58-85-5 Molekylær formel: C10H16N2O3S Molekylvægt (g/mol): 244.31 MDL nummer: MFCD00005541 InChI nøgle: YBJHBAHKTGYVGT-UHFFFAOYNA-N Synonym: biotin,d-biotin,vitamin h,coenzyme r,vitamin b7,bios ii,factor s,bioepiderm,d +-biotin,biodermatin PubChem CID: 171548 ChEBI: CHEBI:15956 IUPAC navn: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentansyre SMIL: OC(=O)CCCCC1SCC2NC(=O)NC12

EDGE
MDL nummer MFCD00005541
PubChem CID 171548
Molekylvægt (g/mol) 244.31
CAS 58-85-5
ChEBI CHEBI:15956
Synonym biotin,d-biotin,vitamin h,coenzyme r,vitamin b7,bios ii,factor s,bioepiderm,d +-biotin,biodermatin
SMIL OC(=O)CCCCC1SCC2NC(=O)NC12
IUPAC navn 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentansyre
InChI nøgle YBJHBAHKTGYVGT-UHFFFAOYNA-N
Molekylær formel C10H16N2O3S
2

2-Iminobiotin, MedChemExpress

MedChemExpress 2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively. 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage.

ENCOMPASS_PREFERRED
3

Biotin, MedChemExpress

MedChemExpress Biotin (Vitamin B7) is a water-soluble B vitamin and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Biotin
Formel vægt 244.31
Opløselighedsinformation DMSO : 100 mg/mL (409.32 mM; Need ultrasonic) ∣H2O : 1 mg/mL (4.09 mM; Need ultrasonic)
Procent renhed 98.0%
Fysisk form Powder
Farve White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 244.31
CAS 58-85-5
Synonym Vitamin B7 Vitamin H D-Biotin
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(O)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
Renhedsgrad noter Research
Molekylær formel C10H16N2O3S
Til brug med (applikation) Metabolism-sugar/lipid metabolism
4

Ibrutinib-biotin, MedChemExpress

MedChemExpress Ibrutinib-biotin is a probe that consists of Ibrutinib linked to biotin via a long chain linker, extracted from patent WO2014059368A1 Compound 1-5, has an IC50 of 0.755-1.02 nM for BTK.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Ibrutinib-biotin
Sundhedsfare 1 H302∣H315∣H319∣H335
Formel vægt 1097.37
Opløselighedsinformation DMSO : 50 mg/mL (45.56 mM; Need ultrasonic)
Procent renhed 98.04%
Fysisk form Oil
Farve Colorless
Grad Research
Anbefalet opbevaring Pure form -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 1097.37
CAS 1599432-18-4
Holdbarhed Pure form -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(CCCC(NCCCOCCOCCOCCCNC(CCCC[C@@H]1SC[C@H](N2)[C@@H]1NC2=O)=O)=O)NCCCCN(C)C/C=C/C(N3CCC[C@@H](N4N=C(C5=CC=C(OC6=CC=CC=C6)C=C5)C7=C(N)N=CN=C74)C3)=O
Renhedsgrad noter Research
Molekylær formel C56H80N12O9S
Til brug med (applikation) Cancer-Kinase/protease