Benzopyraner
Organiske polycykliske forbindelser, der består af en benzen fusioneret med en heterocyklisk pyranring; pyranringe er seksleddede ikke-aromatiske ringe med fem carbonatomer, et oxygenatom og to dobbeltbindinger.
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Deguelin, MedChemExpress
MedChemExpress Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Kemisk navn eller materiale | Deguelin |
|---|---|
| Formel vægt | 394.42 |
| Opløselighedsinformation | DMSO : 100 mg/mL (253.54 mM; Need ultrasonic) |
| Procent renhed | 98.0% |
| Fysisk form | Solid |
| Farve | Light Yellow |
| Grad | Research |
| Anbefalet opbevaring | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molekylvægt (g/mol) | 394.42 |
| CAS | 522-17-8 |
| Synonym | (-)-Deguelin (-)-cis-Deguelin |
| Holdbarhed | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| SMIL | O=C1[C@]2([H])[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC=C14 |
| Renhedsgrad noter | Research |
| Molekylær formel | C23H22O6 |
| Til brug med (applikation) | Cancer-Kinase/protease |
Iclaprim, MedChemExpress
MedChemExpress Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Kemisk navn eller materiale | Iclaprim |
|---|---|
| Formel vægt | 354.4 |
| Opløselighedsinformation | DMSO : 30 mg/mL (84.65 mM; Need ultrasonic and warming) |
| Procent renhed | 99.49% |
| Fysisk form | Solid |
| Farve | Off-White |
| Grad | Research |
| Anbefalet opbevaring | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molekylvægt (g/mol) | 354.4 |
| CAS | 192314-93-5 |
| Synonym | AR-100 |
| Holdbarhed | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| SMIL | NC1=NC=C(CC2=C3C=CC(C4CC4)OC3=C(OC)C(OC)=C2)C(N)=N1 |
| Renhedsgrad noter | Research |
| Molekylær formel | C19H22N4O3 |
| Til brug med (applikation) | COVID-19-immunoregulation |
CU-CPT17e, MedChemExpress
MedChemExpress CU-CPT17e is a potent multi-Toll-like receptor (TLR) agonist that activates TLR3, TLR8, and TLR9.
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Kemisk navn eller materiale | CU-CPT17e |
|---|---|
| Formel vægt | 504.49 |
| Opløselighedsinformation | DMSO : 5 mg/mL (9.91 mM; Need ultrasonic and warming) |
| Procent renhed | 98.0% |
| Fysisk form | Solid |
| Farve | Light Yellow |
| Grad | Research |
| Anbefalet opbevaring | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molekylvægt (g/mol) | 504.49 |
| CAS | 2109805-75-4 |
| Holdbarhed | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| SMIL | O=[N+]([O-])C(C=C1)=CC=C1COC2=CC(C=CC3(CCOCC3)O4)=C4C=C2OCC5=CC=C([N+]([O-])=O)C=C5 |
| Renhedsgrad noter | Research |
| Molekylær formel | C27H24N2O8 |
| Til brug med (applikation) | Cancer-programmed cell death |