RBL2 is a key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 ′Lys-20′ trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a ...
Cat # 16363725
100 µL
Cat # 15734886
0.1 ml
Cat # 16358284
100 µL
Cat # 16336854
100 µl
Cat # 16515641
100 µg
Cat # 16309654
100 µL
Cat # 11561552
100 µg
Cat # 11558103
100 µg
Cat # 11315033
500 µL
Cat # 15915485
100 µg
Cat # 11556263
50 µL
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