missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Proteinanalysereagenser
  4. Bioaktive små molekyler
  5. 17180242

STEMCELL Technologies Zoledronic Acid (Hydrate)

Artikelnummer. 17180242
Encompass_Preferred
Skift visning
Klik for at se tilgængelige muligheder
Mængde:
50 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer. Mængde
17180242 50 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denne vare kan ikke returneres. Se returpolicy
Artikelnummer. 17180242 Leverandør STEMCELL Technologies Leverandørnr. 73572

Please to purchase this item. Need a web account? Register with us today!

Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

Inhibitor of bone resorption; Inhibits farnesyl diphosphate (FPP) synthase

  • Zoledronic acid is a nitrogen-containing bisphosphonate that inhibits farnesyl diphosphate (FPP) synthase (IC50 = 5 nM), thereby preventing protein prenylation and osteoclast-mediated bone resorption (Dunford et al.) In addition, it has a high affinity for hydroxyapatite (Ki = 3.5 μM) which allows it to bind directly to mineralized bone (Nancollas et al.) This product is supplied as the hydrate form of the molecule
  • Inhibits proliferation, angiogenesis, and adhesion to bone, in several cancer cell lines (Li & Davis; Zekri et al.)
  • Inhibits breast and prostate carcinoma cell invasion in vitro (Boissier et al.; Li & Davis)
  • Induces apoptosis of osteoclastoma cells in vitro (Benford et al.)

Tekniske data

CAS 165800-06-6
Synonym Zoledronate
Mængde 50 mg
Molekylær formel C5H10N2O7P2 · H2O
Renhed ≥95%
Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.