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STEMCELL Technologies Zebularine

Artikelnummer. 17160142
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Mængde:
10 mg
Pakningsstørrelse:
10mg
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Artikelnummer. 17160142 Leverandør STEMCELL Technologies Leverandørnr. 72902

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Beskrivelse

Epigenetic modifier; Inhibits DNA methyltransferases (DNMT)

  • Zebularine, a cytidine analog, is a DNA methylation inhibitor that acts by forming a covalent complex with DNA methyltransferases (DNMTs; Zhou et al.)
  • Induces cardiomyocyte differentiation from rat bone marrow mesenchymal stem cells (MSCs; Naeem et al.)
  • Reduces proliferation of the cancer cell lines TK6, Jurkat, KG-1, and HCT116 (Stresemann et al.)
  • Inhibits cell proliferation in T24 bladder carcinoma cells (Ben-Kasus et al.)
  • In combination with the histone deacetylase inhibitor SAHA, reduces cell proliferation and increases apoptosis in pancreatic cancer cell lines (Neureiter et al.)
  • Inhibits cell proliferation and induces apoptosis in human acute myeloid leukemia cells in vitro (Scott et al.)
  • Increases the proportion of cells with cancer stem cell properties in subpopulations of human cancer cells and liver cancer cell lines (Marquardt et al.)

Tekniske data

CAS 3690-10-6
Synonym NSC 309132
Mængde 10 mg
Molekylær formel C9H12N2O5
Renhed ≥98%
Produkttitel
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