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Yoda 1, MedChemExpress

Artikelnummer. 16490078
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16490078 5 mg 5mg
16477608 10 mg 10mg
16453627 50 mg -
16437526 100 mg -
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Artikelnummer. 16490078 Leverandør Medchem Express Leverandørnr. HY18723

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Beskrivelse

MedChemExpress Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda1 induces activation of both Akt and ERK1/2 in endothelial cells (ECs), which is not dependent on Piezo1. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation.

Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda1 induces activation of both Akt and ERK1/2 in endothelial cells (ECs), which is not dependent on Piezo1. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation.

Tekniske data

Kemisk navn eller materiale Yoda 1
Fysisk form Powder
CAS 448947-81-7
Farve White
Mængde 5 mg
Renhedsgrad noter Research
Molekylær formel C13H8Cl2N4S2
Til brug med (applikation) COVID-19-immunoregulation
Opløselighedsinformation DMSO : 15.62 mg/mL (43.97 mM; ultrasonic and warming and heat to 60°C)
SMIL ClC1=C(CSC2=NN=C(C3=NC=CN=C3)S2)C(Cl)=CC=C1
Molekylvægt (g/mol) 355.27
Formel vægt 355.27
Procent renhed 99.83%
Grad Research
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Research purposes only

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