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Tocris Bioscience™ YC 1
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Artikelnummer. 18065692
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18065692 50 mg
18064852 10 mg
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Artikelnummer. 18065692 Leverandør Tocris Bioscience™ Leverandørnr. 4307/50

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Soluble guanylyl cyclase (sGC) activator; induces G1 cell cycle arrest

Nitric oxide-independent activator of soluble guanylyl cyclase (sGC). Significantly elevates cGMP levels and inhibits collagen-stimulated aggregation of washed rabbit platelets (IC50 = 14.6 μM); induces relaxation in denuded phenylephrine-contracted rabbit aortic rings (EC50 = 1.9 μM). Also displays antiproliferative activity in vitro and in vivo by inducing G1 cell cycle arrest in two human hepatocellular carcinoma (HCC) cell lines, and in HCC xenografts in athymic SCID mice. Exhibits low cytotoxicity in non-malignant cells.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 170632-47-0
Molekylær formel C19H16N2O2

Tekniske data

Kemisk navn eller materiale YC 1
Mængde 50 mg
Formel vægt 304.34
Renhed >99%
Molekylvægt (g/mol) 304.35
Produkttitel
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