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Y-26763, Tocris Bioscience™
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Artikelnummer. 18065722
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Artikelnummer. Mængde
18065722 50 mg
18054532 10 mg
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Artikelnummer. 18065722 Leverandør Tocris Bioscience Leverandørnr. 2076/50

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Beskrivelse

Kir6 (KATP) channel opener

Y-26763 is a Kir6 (KATP) channel opener and active metabolite of Y-27152. Relaxes contracted rat aortic rings (IC50 = 0.027 mM) and inhibits glucose-induced insulin secretion in isolated human pancreatic β-cells in vitro. Produces hypotension in spontaneously hypertensive rats and displays cardioprotective properties in dogs following systemic administration in vivo.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 127408-31-5
Molekylær formel C14H16N2O4
Molekylvægt (g/mol) 276.292
InChI nøgle IWTCFIIOUXJOOV-OLZOCXBDSA-N
Synonym unii-q9f3xv8a6x, q9f3xv8a6x, +-3s,4r-n-acetyl-n-hydroxy amino-6-cyano-3,4-dihydro-2,2-dimethyl-2h-1-benzopyran-3-ol, n-3s,4r-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2h-1-benzopyran-4-yl-n-hydroxyacetamide, acetamide, n-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2h-1-benzopyran-4-yl-n-hydroxy-, 3s-trans, n-3s,4r-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl-n-hydroxyacetamide, acetamide,n-3s,4r-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2h-1-benzopyran-4-yl-n-hydroxy, n-3s,4r-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-1-benzopyran-4-yl-n-hydroxyacetamide, d05gpx, n-3s,4r-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl-n-hydroxyacetamide
PubChem CID 121878
IUPAC navn N-[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-N-hydroxyacetamide
SMIL CC(=O)N(C1C(C(OC2=C1C=C(C=C2)C#N)(C)C)O)O

Tekniske data

Kemisk navn eller materiale Y-26763
Mængde 50 mg
Formel vægt 276.29
Procent renhed >98%
Produkttitel
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