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Invitrogen™ WNK1 Polyclonal Antibody
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Artikelnummer. 15925795
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Mængde:
100 μg
Pakningsstørrelse:
100µg
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15925795 100 μg 100µg
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Artikelnummer. 15925795 Leverandør Invitrogen™ Leverandørnr. PA580229

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Beskrivelse

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat testis tissue. IHC: mouse testis tissue, rat testis tissue, human intestinal cancer tissue.

WNK1 serine/threonine kinase is a member of the WNK subfamily. WNK1 may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. WNK plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen WNK1
Applikationer Immunohistochemistry (Paraffin), Western Blot
Klassifikation Polyclonal
Koncentration 500 μg/mL
Konjugeret Unconjugated
Formulering PBS with 5mg BSA and 0.05mg sodium azide
Gene WNK1
Genadgangsnr. P83741, Q9H4A3, Q9JIH7
Gene Alias 6430573H23Rik; EG406236; Erythrocyte 65 kDa protein; HSAN2; HSN2; hWNK1; KDP; KIAA0344; Kinase deficient protein; MGC163339; MGC163341; mKIAA0344; p65; PPP1R167; Prkwnk1; prostate-derived sterile 20-like kinase; protein kinase lysine-deficient 1; Protein kinase with no lysine 1; protein phosphatase 1, regulatory subunit 167; PSK; Serine/threonine-protein kinase WNK1; serine/threonine-protein kinase WNK1 1; serine/threonine-protein kinase WNK1 2; With no K; WNK lysine deficient protein kinase 1; WNK lysine deficient protein kinase 1 isoform; WNK1
Gensymboler WNK1
Værtsarter Rabbit
Immunogen A synthetic peptide corresponding to a sequence in the middle region of human WNK1 (1154-1195aa DNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSED).
Oprensningsmetode Antigen affinity chromatography
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 116477, 232341, 65125
Målarter Human, Mouse, Rat
Indhold og opbevaring -20°C
Produkttype Antibody
Form Lyophilized
Isotype IgG
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